Wednesday, April 24, 2019

The Effects of Metformin on Polycystic Ovarian Syndrome Term Paper

The Effects of Metformin on Polycystic Ovarian Syndrome - Term Paper slipCenter of discussion in this paper is Polycystic Ovarian Syndrome (PCOS) that actually indicates the presence of multiple cysts in the ovaries of reliable women. This naturally impedes the normal ovarian function and also gives rise to a lean of associated conditions in the physiology of much(prenominal)(prenominal) women. The presence of PCOS also induces the patients to develop diabetes mellitus. Metformin has been recognized as an effective medication for PCOS patients. There are a host of genetic, physiological and environmental factors behind the presence of PCOS in women. It has become a real common gynecological condition in most modern women. In the earlier days, physicians used the customary method in the handling of PCOS. This method consisted of suppressing the normal ovarian function of the patients with the help of a number of medicines. Oral contraceptives, progestins and GnRH agonists were prescribed to the patients to improve their physiological functioning. In recent times, the treatment of PCOS has veered towards the insulin sensitivity based treatment of the sickness. Metformin is one such insulin sensitizing agent which mainly aims at reducing the insulin level of PCOS patients and and then generates beneficial effects to deal with their other medical conditions. It has gradually come to be accepted as an integral part of the modern nursing care. The review of the literature first endeavors to understand the emergence and complexness of Polycystic Ovarian Syndrome reflecting on the factors which have made the disease more complex in nature. Secondly, it cites the various conventional approaches, pharmacological and non pharmacological, which have been used in the past in an attempt to curb the incidence of the disease and assesses the efficacy of each. Finally, it focuses on the use of Metformin in the treatment of the disease, outlining the advantages and dis advantages associated with its use in treating Polycystic Ovarian Syndrome in cases of pregnancy as well as in normal cases. Polycystic Ovarian Syndrome PCOS should not in itself be properly described as a disease. Rather, it is observed as a combination of different symptoms, which in turn reflects various ailments. Radosh (2009) observed that Polycystic Ovarian Syndrome is more complex during the reproductive stage of a womens life. Multiple cysts is one of the hallmark of PCOS. The emergence of ovarian cysts is due to the result of hormonal imbalances between the pituitary body and ovarian organs. During the reproductive period, women affected by PCOS tend to have a plethora of problems. These include back-to-back miscarriages, inability to conceive, extreme obesity, excessive hair on the body, face and chest, and prolonged menstruation. The existence of PCOS in women is progressively linked to metabolic dysfunction leading to severe diabetic and cardio-vascular complications. It is further observed that the effect of such complications can give rise to excessive mental stress and loss of self esteem (Radish, 2009). get on Groups Affected by PCOS PCOS affects the female population both in the younger and later years. Ushiroyama, Hosotani, Mori, Yamashita, Ikeda and Ueki(2006) observed that PCOS starts at a young age, revealing hormonal abnormality through symptoms such as menstrual

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